Overview of Mitral Valve Prolapse
The mitral valve is a valve located between the left atrium and left ventricle of the heart. It is responsible for controlling the flow of blood between these chambers, and ensuring that blood flows in the correct direction. Mitral valve prolapse (MVP) is a condition in which the mitral valve does not function properly, and the valve’s flaps, called leaflets, bulge (prolapse) into the left atrium during ventricular contraction (systole).
Causes of Mitral Valve Prolapse
The exact cause of MVP is not known, but it is believed to be related to changes in the connective tissue of the valve. Some potential causes of MVP include:
- Marfan Syndrome: This is a genetic disorder that affects the connective tissue in the body, and is associated with MVP.
- Hypertrophic Cardiomyopathy: This is a condition in which the heart muscle becomes thickened, and is also associated with MVP.
- Rheumatic Fever: This is an inflammatory disease that can damage the heart valves, including the mitral valve, and lead to MVP.
Symptoms of Mitral Valve Prolapse
Many people with MVP do not experience any symptoms, but some may experience:
- Chest pain: This may be a sharp or dull pain that is felt in the chest.
- Shortness of breath: This may be caused by fluid build-up in the lungs.
- Palpitations: This is a feeling of a rapid or irregular heartbeat.
- Fatigue: This may be caused by the heart having to work harder than normal.
Diagnosis and Evaluation of Mitral Valve Prolapse
MVP can be diagnosed using a variety of tests including:
- Echocardiogram: This is a test that uses sound waves to create a moving picture of the heart. It can be used to see the mitral valve and check how well it is functioning.
- Chest X-ray: This can be used to see the size and shape of the heart and check for fluid build-up in the lungs.
- Electrocardiogram (ECG): This is a test that records the electrical activity of the heart. It can be used to check for abnormal heart rhythms.
Treatment Options for Mitral Valve Prolapse
Treatment for MVP depends on the severity of the condition and the symptoms experienced. It may include:
- Medications: Medications such as beta-blockers can be used to control symptoms such as palpitations and chest pain.
- Surgery: In some cases, surgery may be needed to repair or replace the mitral valve.
- Lifestyle changes: Making changes to lifestyle, such as quitting smoking and managing stress, can help to improve the symptoms of MVP.
It is important to note that MVP is usually not a life-threatening condition, and many people with MVP can lead normal lives with proper management and treatment. In case of severe symptoms or complications, it is always best to seek medical attention.
Symptoms of Mitral Valve Prolapse
Mitral valve prolapse (MVP) is a condition in which the mitral valve, a valve located between the left atrium and left ventricle of the heart, does not function properly. MVP can cause a variety of symptoms, some of which are mild and some of which are severe. It’s important to note that many people with MVP do not experience any symptoms at all.
Chest Pain
Chest pain is one of the most common symptoms of MVP. This pain can be sharp or dull and may be felt in the chest or upper abdomen. The pain can be caused by the mitral valve not closing properly, which can lead to blood flowing back into the left atrium. This can cause pressure to build up in the chest, resulting in pain.
Shortness of Breath
Shortness of breath, or dyspnea, is another common symptom of MVP. This can be caused by fluid build-up in the lungs, a condition known as pulmonary edema. When the mitral valve is not functioning properly, blood can flow back into the left atrium and then into the lungs, leading to fluid build-up and shortness of breath.
Palpitations
Palpitations, or a feeling of a rapid or irregular heartbeat, is another symptom of MVP. This can be caused by an abnormal heart rhythm, known as an arrhythmia. MVP can also cause blood to flow back into the left atrium, which can cause the atrium to contract irregularly and lead to palpitations.
Fatigue
Fatigue is another symptom of MVP. This can be caused by the heart having to work harder than normal. When the mitral valve is not functioning properly, the heart has to work harder to pump blood through the valve. This can lead to fatigue and tiredness.
Other symptoms
Other symptoms of MVP may include:
- Dizziness: This can be caused by an abnormal heart rhythm or by blood flowing back into the left atrium and then into the lungs.
- Fainting: This can be caused by an abnormal heart rhythm or by blood flowing back into the left atrium and then into the lungs.
- Cough: This can be caused by fluid build-up in the lungs.
It is important to note that MVP symptoms can vary from person to person and may also be caused by other conditions. If you experience any of these symptoms, it is important to seek medical attention to determine the cause.
Causes of Mitral Valve Prolapse
Mitral valve prolapse (MVP) is a condition in which the mitral valve, a valve located between the left atrium and left ventricle of the heart, does not function properly. The exact cause of MVP is not known, but it is believed to be related to changes in the connective tissue of the valve.
Marfan Syndrome
Marfan Syndrome is a genetic disorder that affects the connective tissue in the body. Connective tissue is the tissue that holds the body’s cells, organs, and other structures together. This disorder can cause the mitral valve to become elongated, which can lead to MVP.
Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy is a condition in which the heart muscle becomes thickened. This thickening can affect the mitral valve and lead to MVP. It is important to note that this condition is also inherited genetically.
Rheumatic Fever
Rheumatic fever is an inflammatory disease that can damage the heart valves, including the mitral valve, and lead to MVP. This disease is caused by a streptococcal infection.
Other Causes
Other causes of MVP can include:
- Connective tissue disorders: Other connective tissue disorders, such as Ehlers-Danlos syndrome, can also cause MVP.
- Infections: Certain infections, such as Lyme disease, can also cause MVP.
- Drugs: Certain drugs, such as appetite suppressants, can also cause MVP.
It is important to note that MVP can also occur in people with no known cause. MVP can also be associated with other heart conditions such as mitral stenosis or mitral regurgitation which can cause complications.
Diagnosis and Evaluation of Mitral Valve Prolapse
Mitral valve prolapse (MVP) is a condition in which the mitral valve, a valve located between the left atrium and left ventricle of the heart, does not function properly. MVP can be diagnosed using a variety of tests, which help to determine the condition of the mitral valve and the severity of the prolapse.
Echocardiogram
An echocardiogram is a test that uses sound waves to create a moving picture of the heart. This test can be used to see the mitral valve and check how well it is functioning. An echocardiogram can also be used to determine the amount of blood flowing through the valve, and the size of the prolapse.
Chest X-ray
A chest x-ray can be used to see the size and shape of the heart and check for fluid build-up in the lungs. Fluid build-up in the lungs can be a sign of mitral valve prolapse.
Electrocardiogram (ECG)
An electrocardiogram (ECG) is a test that records the electrical activity of the heart. It can be used to check for abnormal heart rhythms. MVP can be associated with arrhythmias, which can be detected on ECG.
Cardiac Catheterization
Cardiac catheterization is a procedure in which a thin, flexible tube called a catheter is inserted through an artery or vein in the leg or arm and then guided to the heart. This procedure can be used to measure the pressure in the heart and check the blood flow through the mitral valve.
Cardiac MRI
Cardiac MRI is a test that uses a powerful magnetic field, radio waves, and a computer to create detailed images of the heart and its blood vessels. The test can be used to evaluate the mitral valve, the size and shape of the ventricle and detect any fluid buildup in the lungs.
It is important to note that MVP can have varying degrees of severity and symptoms. Therefore, it is important for the diagnosis and evaluation to be done by a cardiologist. In addition, if MVP is suspected, a patient should be monitored over time to determine if the condition is progressing or if any treatment is needed.
Treatment Options for Mitral Valve Prolapse
Mitral valve prolapse (MVP) is a condition in which the mitral valve, a valve located between the left atrium and left ventricle of the heart, does not function properly. The treatment of MVP will depend on the severity of the condition and the symptoms experienced by the patient.
Medications
Medications can be used to control symptoms such as palpitations and chest pain. Some of the medications that can be used include:
- Beta-blockers: These medications can be used to slow the heart rate and control palpitations.
- Diuretics: These medications can be used to remove fluid from the body and reduce shortness of breath.
- Anticoagulants: These medications can be used to prevent blood clots from forming, especially in patients with severe MVP.
Surgery
In some cases, surgery may be needed to repair or replace the mitral valve. The type of surgery will depend on the individual case.
- Valvuloplasty: This is a procedure in which the surgeon uses a catheter to repair the mitral valve. It can be used to treat MVP caused by thickened valve leaflets.
- Valve replacement: This is a procedure in which the surgeon replaces the damaged mitral valve with an artificial valve. This procedure can be done through open-heart surgery or through a minimally invasive approach.
Lifestyle Changes
Making changes to lifestyle, such as quitting smoking and managing stress, can help to improve the symptoms of MVP. In addition, maintaining a healthy diet, regular exercise and maintaining a healthy weight can also help to improve the symptoms of MVP.
It is important to note that MVP is usually not a life-threatening condition, and many people with MVP can lead normal lives with proper management and treatment. However, in case of severe symptoms or complications, it is always best to seek medical attention. Regular follow-up with a cardiologist is also important to monitor the condition and make any necessary adjustments to treatment.
Sources & references used in this article:
- Current concepts in mitral valve prolapse—diagnosis and management (PM Shah – Journal of cardiology, 2010 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S0914508710001309 - Prevalence and clinical outcome of mitral-valve prolapse (LA Freed, D Levy, RA Levine, MG Larson… – … England Journal of …, 1999 – Mass Medical Soc)
https://www.nejm.org/doi/full/10.1056/NEJM199907013410101 - Relation between clinical features of the mitral prolapse syndrome and echocardiographically documented mitral valve prolapse (RB Devereux, R Kramer-Fox, WT Brown… – Journal of the American …, 1986 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S0735109786804156 - Mitral valve prolapse (E Hayek, CN Gring, BP Griffin – The Lancet, 2005 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S0140673605178696