Introduction to Adult Onset Hives: Symptoms and Diagnosis
Hives, also known as urticaria, are a common skin condition characterized by raised, red, and itchy welts on the skin. They can appear anywhere on the body and can vary in size and shape. Hives can be caused by a variety of factors, including allergies, infections, and autoimmune diseases. Adult onset hives, or hives that develop in adulthood, can be particularly difficult to diagnose and treat.
Symptoms of Adult Onset Hives
- Itching: Itching is the most common symptom of hives and can range from mild to severe.
- Redness: Hives appear as raised, red welts on the skin. They can be round or have irregular shapes.
- Swelling: Some hives can cause swelling, particularly around the eyes and lips.
- Fever: In some cases, hives can be accompanied by fever, fatigue, and general malaise.
- Anxiety: Some people may experience a feeling of tightness in the chest, difficulty breathing, or anxiety when they have hives.
Diagnosis of Adult Onset Hives
Diagnosis of adult onset hives typically begins with a physical examination and a review of the patient’s symptoms and medical history. The following tests may be used to help diagnose the condition:
- Skin test: A skin test may be done to determine if the hives are caused by an allergic reaction.
- Blood test: A blood test may be done to check for autoimmune disorders or other underlying medical conditions that can cause hives.
- Patch test: A patch test may be done to identify any specific allergens that may be causing the hives.
It is important to note that some cases of adult onset hives may not have an identifiable cause, and may be classified as idiopathic urticaria. In these cases, treatment may focus on managing symptoms.
It is important to see a healthcare provider if you have symptoms of adult onset hives, especially if the hives are accompanied by difficulty breathing or swelling of the face, lips, tongue, or throat. These symptoms can be a sign of a severe allergic reaction and require immediate medical attention.
In conclusion, Adult onset hives can be a frustrating and difficult condition to diagnose and treat. A proper diagnosis is essential in identifying the underlying cause and providing the appropriate treatment. If you have symptoms of hives, it is important to see a healthcare provider to determine the cause and develop an effective treatment plan.
Allergic Causes of Adult Onset Hives: Food Allergies and Medications
Allergic reactions are a common cause of adult onset hives. An allergic reaction occurs when the body’s immune system mistakenly identifies a harmless substance, such as a food or medication, as a threat and produces antibodies to fight it. This response can cause a variety of symptoms, including hives.
Food Allergies and Adult Onset Hives
Certain foods can trigger hives in some people. The most common food allergens that can cause hives include:
- Nuts: Peanuts, almonds, and other nuts are a common cause of food-induced hives.
- Seafood: Fish and shellfish can also cause hives in some people.
- Eggs: Eggs are another common allergen that can cause hives.
- Cow’s milk: Some people may develop hives after consuming cow’s milk.
Symptoms of food-induced hives typically appear within minutes to a few hours after eating the offending food. In some cases, hives may be accompanied by other symptoms such as stomach cramps, diarrhea, and difficulty breathing.
Medications and Adult Onset Hives
Certain medications can also cause hives in some people. These include:
- Aspirin: Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) can cause hives in some people.
- Antibiotics: Some antibiotics, such as penicillin, can cause hives.
- Blood pressure medications: Some blood pressure medications, such as ACE inhibitors, can cause hives.
Symptoms of medication-induced hives typically appear within a few hours to a few days after starting the medication. In some cases, hives may be accompanied by other symptoms such as itching, swelling, and difficulty breathing.
It’s important to note that not everyone who takes these medications will develop hives. In addition, hives may appear as a side effect of a medication even if a person is not allergic to it.
In conclusion, food allergies and medications are common causes of adult onset hives. If you suspect that a certain food or medication is causing your hives, it is important to see a healthcare provider to confirm the diagnosis and develop an appropriate treatment plan. Avoiding the offending food or medication is the most effective way to prevent hives from recurring. If hives are accompanied by difficulty breathing or swelling of the face, lips, tongue, or throat, seek medical attention immediately, as these symptoms can be a sign of a severe allergic reaction.
Non-Allergic Causes of Adult Onset Hives: Infections and Autoimmune Diseases
Not all cases of adult onset hives are caused by allergies. In some cases, hives may be caused by other underlying medical conditions such as infections and autoimmune diseases.
Infections and Adult Onset Hives
Certain infections can cause hives as a symptom. These include:
- Viral infections: Viral infections such as the common cold, flu, and hepatitis can cause hives.
- Bacterial infections: Bacterial infections such as strep throat and urinary tract infections can also cause hives.
- Parasitic infections: Parasitic infections such as scabies and lice can cause hives.
Symptoms of infection-induced hives typically appear within a few days of contracting the infection and may be accompanied by other symptoms such as fever, fatigue, and general malaise.
Autoimmune Diseases and Adult Onset Hives
Autoimmune diseases are conditions in which the body’s immune system mistakenly attacks healthy cells and tissues. These diseases can cause a variety of symptoms, including hives. The following autoimmune diseases have been associated with hives:
- Lupus: Lupus is a chronic autoimmune disease that can cause a variety of symptoms, including hives.
- Rheumatoid arthritis: Rheumatoid arthritis is an autoimmune disease that causes inflammation in the joints and other parts of the body. It can also cause hives.
- Scleroderma: Scleroderma is a chronic autoimmune disease that causes hardening and thickening of the skin. It can also cause hives.
Symptoms of autoimmune disease-induced hives typically appear gradually and may be accompanied by other symptoms such as joint pain, fatigue, and general malaise.
In conclusion, infections and autoimmune diseases are non-allergic causes of adult onset hives. If you suspect that you have an underlying infection or autoimmune disease, it is important to see a healthcare provider to confirm the diagnosis and develop an appropriate treatment plan. Treatment for infection-induced hives typically involves treating the underlying infection. Treatment for autoimmune disease-induced hives typically involves managing the symptoms and slowing the progression of the disease. In cases of autoimmune diseases, it is important to see a rheumatologist or other specialist for proper diagnosis and treatment.
Managing Adult Onset Hives: Treatment and Prevention
Adult onset hives can be a frustrating and difficult condition to manage. The treatment and prevention of hives will depend on the underlying cause.
Treatment of Adult Onset Hives
The treatment of adult onset hives will depend on the underlying cause, but may include:
- Antihistamines: Antihistamines can be used to relieve itching and other symptoms of hives. They work by blocking the action of histamine, a chemical that is released during an allergic reaction.
- Corticosteroids: Corticosteroids can be used to reduce inflammation and itching associated with hives. They can be taken orally or applied topically.
- Immunomodulators: Immunomodulators can be used to suppress the immune system in cases of autoimmune diseases that causes hives.
In cases where the underlying cause of hives cannot be determined or is not treatable, the focus will be on managing symptoms.
Prevention of Adult Onset Hives
Preventing adult onset hives will depend on the underlying cause, but may include:
- Avoiding triggers: If you know that certain foods or medications trigger your hives, avoid them.
- Taking preventive medication: If you have a history of hives, your healthcare provider may recommend taking preventive medication to reduce your risk of having a flare-up.
- Managing underlying medical conditions: If you have an underlying medical condition such as an autoimmune disease that is causing your hives, managing that condition can help reduce your risk of having a flare-up.
In conclusion, the treatment and prevention of adult onset hives will depend on the underlying cause. If you suspect that you have hives, it is important to see a healthcare provider to determine the cause and develop an appropriate treatment plan. In some cases, avoiding triggers and taking preventive medication can help reduce the risk of having a flare-up. Managing underlying medical conditions can also help to reduce the risk of hives in some cases.
New research: Understanding the underlying mechanism of adult onset hives
Hives, also known as urticaria, are a common skin condition characterized by raised, red, and itchy welts on the skin. They can appear anywhere on the body and can vary in size and shape. While the exact underlying mechanism of hives is not fully understood, new research is shedding light on the causes and potential treatments of this condition.
Role of Histamine in Hives
Histamine is a chemical that is released by the immune system during an allergic reaction. It is well established that histamine plays a key role in the development of hives. When histamine is released, it causes blood vessels to dilate and leak fluid, resulting in the characteristic red and itchy welts of hives. Antihistamines, which block the action of histamine, are commonly used to relieve the symptoms of hives.
Role of Mast Cells in Hives
Mast cells are a type of immune cell that play a key role in the development of hives. Mast cells are found in the skin and other tissues, and when activated, they release histamine and other chemicals that cause inflammation and itching. New research is investigating the role of mast cells in the development of hives and potential new treatments that target mast cells.
Role of Autoimmunity in Hives
Autoimmunity is a condition in which the body’s immune system mistakenly attacks healthy cells and tissues. Recent research suggests that autoimmunity may play a role in some cases of adult onset hives. Studies have found that some people with hives have antibodies against their own skin cells, which suggests that the immune system is mistakenly attacking the skin. This research is leading to the development of new treatments that target the underlying autoimmune process in hives.
In conclusion, new research is shedding light on the underlying mechanisms of adult onset hives. The role of histamine, mast cells, and autoimmunity are being actively researched and new treatments targeting these mechanisms are being developed. While the exact cause of adult onset hives is not fully understood, it is believed that a combination of genetic, environmental and immune factors play a role. Further research is needed to fully understand the underlying mechanisms of this condition and develop new and effective treatments.
Sources & references used in this article:
- The role of penicillin in benign skin rashes in childhood: a prospective study based on drug rechallenge (JC Caubet, L Kaiser, B Lemaître, B Fellay… – … and clinical immunology, 2011 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S009167491001273X - 1 nonimmediate allergic reactions induced by drugs: Pathogenesis and diagnostic tests (MJ Torres, C Mayorga, M Blanca – … allergology & clinical immunology, 2009 – jiaci.org)
https://www.jiaci.org/issues/vol19issue2/1.pdf - Drug hypersensitivity reactions documented in electronic health records within a large health system (A Wong, DL Seger, KH Lai, FR Goss… – … and Clinical Immunology …, 2019 – Elsevier)
https://www.sciencedirect.com/science/article/pii/S2213219818307517